The wide receiver walked off with medical staff after catching a 16-yard pass from Brock Purdy.
Mike Evans went down with a leg injury late in the first half and limped to the locker room with help from a member of the medical staff. Evans had just hauled in a 16-yard catch from Brock Purdy when he hit the ground and appeared to be in pain, prompting medical personnel to come out and check on him.
Evans had been trending toward playing after being listed as questionable for Week 6, and he was confirmed active ahead of kickoff. His exit before halftime leaves his status for the rest of the game uncertain.
No further details on the severity of the injury were immediately available. The 49ers will have to navigate the remainder of the matchup without clarity on whether Evans can return.