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NFL Week 6 picks roll in as contenders face early reality check

Thursday night kicks things off with Seahawks at Broncos before a slate that includes Cowboys-Packers and Bills-Raiders.

Week 6 has arrived, and the usual flood of expert picks suggests nobody is fully sure what to make of this NFL season. The early weeks have been less about teams playing great and more about previously trusted contenders looking shaky, which has thrown off plenty of prediction sheets.

The week opens Thursday night with Seahawks at Broncos, a matchup between two 2025 top seeds who are, as one analyst dryly noted, one loss away from matching last year's entire loss total. Primetime also features Packers-Cowboys and 49ers-Commanders, while the broader slate includes Bills at Raiders and Panthers at Eagles among the headline bouts.

The Bengals, Dolphins, Lions, and Vikings get a break this week with byes, leaving pickers to sort through the rest of the league. At least one outlet's tracker admitted a rough patch with primetime games, whiffing on every night game across the past two weeks, though a stronger showing in the rest of the games kept the overall record respectable, if unspectacular.

With odds and spreads out across the full slate of games, the picks are in. Now the teams just have to go play them.

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